A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies
نویسندگان
چکیده
منابع مشابه
A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies.
mRNP remodeling events required for the transition of an mRNA from active translation to degradation are currently poorly understood. We identified protein factors potentially involved in this transition, which are present in mammalian P bodies, cytoplasmic foci enriched in 5' --> 3' mRNA degrading enzymes. We demonstrate that human P bodies contain the cap-binding protein eIF4E and the related...
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ژورنال
عنوان ژورنال: RNA
سال: 2005
ISSN: 1355-8382
DOI: 10.1261/rna.2340405